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How Unisom® tablets work

Unisom® Extra Strength tablets contains diphenhydramine hydrochloride. It is indicated for the relief of occasional nighttime sleeplessness due to overwork or fatigue.

Unisom® Sleep® packshot

Extra Strength – Tablets

Unisom® helps reduce difficulty falling asleep.

Where to buy Unisom®

How to take Unisom®

Adults and children 12 years of age and over:

  • Take 1 tablet at bedtime if needed, or as directed by a doctor.
    • In some persons, persisting drowsiness may be experienced with a dose of 50 mg, in which case the dose should be subsequently reduced to 25 mg.
  • Do not exceed the recommended dosage except on the advice of a doctor.

KEEP OUT OF THE REACH OF CHILDREN. Do not use with other products containing this medicinal ingredient. Doing so may result in accidental overdose.

Learn more about getting to sleep, staying asleep, and waking up refreshed.

Visit sleep tips and tools section


Medicinal ingredient:

  • Each Unisom® Extra Strength tablet contains 50 mg of diphenhydramine hydrochloride.

Non-medicinal ingredients:

  • Colourant
  • Dibasic calcium phosphate dihydrate
  • Magnesium stearate
  • Microcrystalline cellulose
  • Opadry
  • Sodium starch glycolate


Available in 20 tablets.

Unisom® Sleep® packshot

Warnings and contraindications
  • For occasional use only. If sleeplessness persists continuously for more than 2 weeks, consult a doctor. Insomnia may be a symptom of a serious underlying medical illness.
  • Do not take this product if you have glaucoma, asthma, chronic lung disease, difficulty in urination due to an enlargement of the prostate gland, or if you are pregnant or breastfeeding, unless directed by a doctor.
  • Talk to a doctor or pharmacist before using this product if you are currently taking a prescription drug or other medication.
  • Not to be used by elderly patients who experience confusion at nighttime. These drugs may produce excitation rather than sedation in the elderly and should be avoided in this age group.
  • May cause drowsiness. Do not drive or engage in activities requiring alertness.
  • Avoid alcohol.
  • In case of accidental overdose, contact a poison control centre or doctor immediately.
  • KEEP AT ROOM TEMPERATURE IN A DARK, DRY PLACE (between 15 °C and 30 °C).

Visit our sleep tips and tools section to learn more about getting to sleep, staying asleep and waking up refreshed.

Visit sleep tips and tools section